Drug treatment of uterine fibroids
This has to be the talk about the pathogenesis of uterine fibroids. Past that its occurrence and estrogen, which includes male hormone testosterone propionate treatment, to fight; or estrogen receptor blocker tamoxifen to reduce estrogen’s role in it, but the effect of these drugs is not satisfactory . Filicori 1983 Creative GnRH-a (Gonadotropin releasing hormone agonist) therapy it. Its mechanism is linked through a series of pharmacological effects, resulting in hypogonadism (low estrogen environment similar to their drug-induced removal of ovaries), and the uterus and fibroids reduced blood flow, and finally the fibroids shrink. Significantly reduce the effect of the drug it is difficult to compare with previous drugs. However, the drug prices are high and need daily intramuscular treatment period of up to 3-6 months, limiting its widespread use. In recent years, with the rapid development of medical science, that it is also related to the occurrence and progesterone. According to this mechanism, first of all in 1993, Murphy and progesterone receptor antagonist Ru486 (mifepristone domestic drug name) for the treatment of it, and to block progesterone’s role in it, and achieved satisfactory results. According to recent literature, mifepristone and GnRH-a comparison, the reduction of its efficacy is similar, but its light and low incidence of side effects, relapse rate after treatment is lower than the latter. This medicine is tablets, daily oral 1 to, the price is low, which has allowed easy for the patient receiving the drug, easy to spread.
Clinical use of this drug that has a different degree of fibroids after treatment reduced symptoms of anemia, red blood cells, hemoglobin targets were back to normal. The drug treatment of uterine fibroids especially applies to the following two conditions: first, women with menopause, it can be reduced after treatment, some experts believe that there is the role of early menopause. On menopausal dysfunctional uterine bleeding accompanied by a drug can be said that the three had, the month after treatment stopped by the vast majority of patient, so that bleeding stopped (after the end of treatment, usually within six weeks recovery period). Second, patients with severe anemia great, so use of this drug before surgery fibroids shrink, easy-to-womb surgery to reduce bleeding, which can make surgery without blood transfusion or less blood transfusion. Department of reasons for infertility caused by uterine fibroids, the fibroids shrink after treatment, uterine fibroids can be excised as a simple technique to retain the uterus, creating conditions for the birth.
Since mifepristone for the treatment of uterine fibroids, there have been considerable portion of the surgery relieved the pain patient, but the drug must have under the guidance of experienced physicians choose to use. In clinical application must be strictly and carefully control their indications and contraindications. Associated with asthma, angina, ulcerative colitis, arrhythmia, heart failure, adrenal insufficiency and other conditions were banned.
Frequently Asked Questions
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QUESTION:
Has anyone tried any natural cures for Uterine Fibroids? & Did it really work?
I am concerned that I may have uterine fibroids. My period has changed signifcantly from my norm of 3 days of light bleeding to 1 day of spotting, 2 days of very heavy bleeding (leaking through super plus tampon ever 2 hours), 2 days of regular bleeding and another 2 days of spotting for a total of 7 days now. My period has also changed from every 28 days to every 26 days. Each month my period has gotten longer and heavier. My mother had fibroid tumors and had to have a hysterectomy. It is my understanding fibroids are hereditary. I would like to know about natural obtainable cures that actually work.
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ANSWER:
i suffer from uterine fibroids, as did my mother, older sister, and 4 of my 1st cousins. one natural cure that i saw and only used once was Cheyenne pepper. one teaspoon at nite in a full glass of water. it is a very hot nasty taste. i battled fibroids for maybe 10 yrs. before i ended up in the er with hemorrhage. i didn’t have a hysterectomy. i had a myomectomy. they cut the fibroid off the outside of my uterus. i have a cut from my naval down, i was in the hospital for 3 days and out of work for 6 wks. the 1st 2 periods were bad and then the were great, but that only can last 6 yrs, its been 8 for me, I’m now starting to have problems again. I’m 48 now and if i have to be cut again i will just have the hysterectomy. a co-worker had a myomectomy, and she went on to have 2 full-term healthy babies. i considered my age at the time. you can get a book of home remedies at a major book store, try some of what you may find in them. good luck! in short do what’s best for you and your lifestyle. you have to live with the results.
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QUESTION:
Can uterine fibroids happen to 16 year olds?
I’m quite worried, It hurts most times I have sex and afterwards..I have had a period for much longer than usual and I’ve had some spotting too…I’ve always had bladder problems but they have become alot worse lately,,,these are some of the syptoms of uterine fibroids but can someone of my age get this? And if not then what could it be? =/-
ANSWER:
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QUESTION:
Uterine fibroids, pain, heavy bleeding and irregular periods?
I have multiple large and small fibroids, severe endometriosis, severe adhesions (they thought I’d had chemo). I used to have very regular periods but they are now irregular and heavy with a long pms time around when I expect a period. I was getting one heavy one about every other month having to change pads every 15 minutes for one day of it. And a lighter one in between with alot of spotting. But sometimes I can have pms symptoms like I’m starting and not start for a couple weeks. (They say it’s inoperable.) Is this common? What should I be worried about? What can I do?-
ANSWER:
I had this same problem in 2005, I experienced heavy bleeding and it continued for about a week, quit with just spotting and then back to bleeding again. This was so bad it put me in a very weak state and finally decided to visit obgyn and had blood test and ultra sound done. I was so low on blood that I had to have 4 pints replaced due to so much blood loss. The ultra sound showed a fibroid tumor. I had a total abdominal hysterectomy in September 2005 and the tumor removed. The fibroid tumor was causing the main problem for me, making my periods unbearable. Now I feel fine health wise, my blood count is back up, but of course I went straight to menopause, but I’m handling it the best I can. I wish you luck, have your blood checked for anemia and an ultra sound to see where and how large the fibroids are.
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QUESTION:
Anyone had uterine polyps/fibroids? Symptoms?
Has anyone had uterine polyps or fibroids. My doctor is thinking this is what I might have. I am just waiting to go have an ultrasound done in early January. What were your symptoms? I have spotting a week after my period, slight, slight cramping, frequent urination and a feeling of fullness in my abdomen. Any advice is appreciated! Thanks-
ANSWER:
I had huge uterine fibroids. My symptoms were
heavy bleeding during period, period stayed for 10-12 days
Anemia
Weakness
I got pregnant with the fibroids and in last July doctors removed my uterus while doing my Cesarean.
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QUESTION:
Why spotting before period? Past 3 !!!!!?
For the past 3 periods, I spotted for about 2 days before I started my period. My periods started on March 20, April 18, and May 15 (this does not include the spotting).I was reading that one common cause of spotting several days before the menstrual cycle is due is low progesterone, uterine fibroids, endometriosis, birth control pills (not on any), or sexually transmitted diseases and some cancers.
I also been having like these weird cramps where I have to stay still until they go away because it been painful to move.
Please should I be concerned that something serious is wrong. I have an appt. on the 1st of June with ob/gyn. Can somebody give me some advice on what could be causing this?
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ANSWER:
I’m not sure if this is cause but I did spot alot before my period or some months it just doesn’t come but until 5/19/2007 i’ve experienced the worst pain in lower left abdomen throughout my back and legs and said I had Ovarian cysts…I’m still researching abbout it sounds common and my follow up Appt.. is tommorrow because I was in ER overnight…I’m not sure if this helps but the spooting sounds familiar to mines…I mean the symptoms for Ovarian cysts are irregular periods,pain in the abdomen,pain during intercourse I mean there’s more but just to name a few….. i can research yourself but to share mines…God Bless and if need more info…please don’t hesitate….
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