Lupron
Hormones are naturally occurring chemicals released from one part of the body that affect other parts of the body in the exocrine and 00004000 endocrine gland systems. Only a small amount of hormone is required to affect necessary changes. During the latter half of the last century, man made hormones have been used to alter bodily processes in a variety of ways, particularly with birth control and aiding cancer treatments.
Lupron is a popular man-made hormone used to control the production of testosterone in men and estrogen in women. This particular hormone is known as a gonadotropin-releasing hormone analog (GnRH analog), which down-regulates the gonadotropin secretion as long as the drug is administered. This effect minimizes both the production of testosterone in men and estradiol in women.
Conditions Treated with Lupron
Lupron injection was first approved by the FDA in 1985 for use to help treat advanced prostate cancer. Since that time, it has also been approved to treat the following conditions as well:
- Endometriosis or fibroids
- Precocious (early) puberty in both male and female children
It is important to remember that Lupron only treats the symptoms of cancer; it does not cure cancer.
Contraindications for Lupron Treatment
Lupron should not be prescribed to women who are pregnant or hope to become pregnant. Women who are breast-feeding should also avoid Lupron treatments. Allergies or hypersensitivity to the following similar drugs should preclude its use:
- Leuprolide
- Buserelin
- Goserelin
- Histrelin
- Nafarelin
Dosage adjustments or special tests may be required for people with the following conditions:
- Osteoporosis, personal or family history
- Undergoing steroid treatments
- Epilepsy
- Asthma
- Migraines
- Heart disease
- Kidney disease
- Depression
Side Effects of Lupron
As with all drugs, serious side effects may result in additional personal injury and even death. Physicians need to ensure proper diagnoses and treatment plans to minimize the risks to their patients. Understanding the potential side effects and detecting problems early help minimize medical negligence on their part. Some of the serious side effects of Lupron include:
- Birth defects
- Bone pain
- Swelling and rapid weight gain
- Lightheadedness
- Problems urinating
- Sudden headache
Other complications may occur and should be known or researched by the treating physician.
Lupron Litigation
Hormone therapy is big business for big drug companies. While they claim to create drugs that are safe and effective, many times the drugs do not seem to be safe enough. The manufacturer of Lupron was convicted of price fixing and criminally charged with fraudulent drug pricing and marketing concerning Lupron. A company that paid out 5 million in damages to settle the criminal and civil charges would probably not hesitate to cut corners in developing a safe drug.
Pharmaceutical litigators defend innocent victims of these mega-corporations whose only concern is their profits. Lawsuits and tort law are the only recourse for seeking compensation for damages caused by callous and uncaring big business.
Frequently Asked Questions
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QUESTION:
Lurpon Injection vs.Myomectomy–Immediate Advice Needed!?
I just turned 26 and was diagnosed with uterine fibroids (25cm-very large!) My OB-Gyn has ordered my a Lupron Injection (scheduled for Friday 12/08/06) it is suppose to shrink the fibroids by pushing me into early menopause and save my fertility-I have no children as of yet, but my dream is to have my own family one day. I have read many horrible reports on Lupron and have done a little reading up on alternatives and came across Myomectomy. I read that they can take the fibroids out of uterus no matter the size, #, or location—This seems much better of an option for me. If anyone has had this done, please tell me your experiences. I kind of feel obligated to get the injection because he already ordered it for me and it is very expensive-I do not want him to deny me as a patient if I refuse it and bring up this other option. Someone please give me advice, this is all new to me and I am scared to death and in alot of pain! I do not know what I need to do or what to say to my Dr. – TY-
ANSWER:
Again, you do not need to feel obligated to having the lurpon injection just because your Doc has ordered it. Before he/she ordered it, he/she should have gone through all the options with you, and taken into consideration, the fact that you would like to bear children. If you go into early menopause, how can you bear children? My advice is for you to visit this excellent website and compare all the alternative ways your Myoma’s can be treated.http://www.myomectomy.net/
I wish you well and good luck.
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QUESTION:
Fibroids/Adenomyoma?
I am 29 with no children. I have always had a very regular period until a few years ago. I started to get night sweats and gradually longer, heavier periods. This past period (which is STILL continuing) started on Feb 8th! I went to my OBG on Monday who felt my uterus and said it was enlarged. I have had an ultra sound in the past which shows I have a fibroid tumor 3 cm in diameter. So her suspicion is that either the fibroid has gotten larger or I have this adenomyoma in which your uterine lining thickens and grows into itself.
She suggested another set of ultrasouunds, followed by Lupron injections to shrink it then surgery to shave it away.
I am into naturally healing and to be honest I will go for the ultra sounds to see whats up, but I probably will not concent to surgery or hormones. My main goal is to preserve my fertility.
Has anyone gone through this that can offer any advice?
No jerks please.-
ANSWER:
If you want to try and reduce fibriods naturally, avoid:
Birth control pills, Hormone replacement drugs, condom spermicides, Conventional personal care products, particularly cosmetics, Plastic cookware, Growth hormones found in factory-farmed animal products, Pesticides and herbicides, DDT, PCBs – polychlorinated biphenyls, and foaming agents in soaps and detergentsMake sure you are at your ideal weight, not overweight.
And reduce stress in your life.
Sometimes going on a water fast, for a period of time eating nothing and drinking only water, can help.
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QUESTION:
adenomyosis w/fibroids?
I am 29 with no children. I have always had a very regular period until a few years ago. I started to get night sweats and gradually longer, heavier periods. I had an ultra sound last week which shows I have either a fibroid tumor alone or with an adenomyosis 9 cm in diameter. So her suspicion is that either the fibroid has gotten larger or I have this adenomyoma in which your uterine lining thickens and grows into itself.
She suggested another set of ultrasouunds, followed by Lupron injections to shrink it then surgery to shave it away.
I am into naturally healing and to be honest I will go for the ultra sounds to see whats up, but I probably will not consent to surgery or hormones. My main goal is to preserve my fertility.
Has anyone gone through this that can offer any advice?-
ANSWER:
O my God! I had the same problem. I’m 28 now. My period was regular too. But bleeding gradually increased within a short time. I was so anemic. My ultrasound showed i had multiple huge fibroids with adenomayoma. I was not even married then. doctor gave to 4 shots of luprone for 4 months then did my surgery, removed 28 of them. but my bleeding continued after the surgery and the fibroids grew again within a short time.
God was kind to me and I got pregnant after 2 years of that surgery. my fibroids were huge when i got pregnant.
Although the baby was born premature, she is fine now.
finally i got rid from heavy bleeding as my uterus has been removed as well. Doctors tried much to save it but it was not possible,
I hope your case is not so bad like me. I will suggest you to get pregnant soon, my experience says so. bleeding can do a lot of harm. I remember i couldn’t go out on those days, count do any work properly, i was weak.
Good luck.
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QUESTION:
Is it necessary to take hormone replacement’s while on Lupron Depot even if you don’t have any symptoms?
I was diagnosed about 3 months ago with 3 fibroids in my uterus, so large they told me I was “about 18 weeks”! I was informed that the soonest I could get surgery was in June so the doctor suggested I take Lu pron to ease my pain, stop the growth and lighten my symptoms of which were constant pain and pressure on my bladder, my bowel and horrible cramps. Anyhow, I got the Lu Pron injection a little more than a month ago and was told to wait a month then start taking a prescription of replacement hormones. Estrogen and Progesteron. Question is, If I feel great, better then I felt in years, with no side effects to complain about, just very light headaches and barely noticable warm flashes, is it necessary for me to take the hormones?
I’ve only heard horrible things about Lupron, but I have to say, I feel great!!-
ANSWER:
Yes, especially if your gyno tells you to and prescribes you the hormone replacements.
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Why is my cycle so heavy and lasting over 3 weeks since I had my 1st Lupron injection in August 2013. My cycle started 3 weeks ago and I’m still bleeding heavily and passing blood clots (huge ones)? Is this normally what happens after taking your 1st dosage of Lupron?